Research and Prognosis on Alzheimer's Disease
Rudolph C. Hatfield, PhD., edited by Kathryn Patricelli, MATreatment Research
At the time of this writing there are well over 100 different medications being investigated in research trials for treating Alzheimer's disease. These medications are at different stages in the research process and:
- The majority of these drugs are what are called modifying therapies. These are hoped to be able to change or alter how the disease progresses.
- A smaller number are cognitive enhancers. These are designed to improve cognitive functions like memory or attention.
- An even smaller number are symptomatic agents. This means that they just work on specific symptoms like agitation, hallucinations (seeing or hearing things that are not there), etc.
The process of approving drugs is often lengthy and consists of many steps. Initial steps are designed to test the safety of the drug. Then the next steps test to see if the drug works or does what it is supposed to do. The final two steps continue with evaluating its safety and effectiveness, as well as how it works when released on the market. Even though there are hundreds of drugs currently in development for Alzheimer's disease, it is a good bet that very few of them will get approval.
Other research that may assist in the development of treatment for Alzheimer's disease includes genetic research. This research is consistently uncovering new genetic associations that may lead to the development of Alzheimer's disease in some people. However, the path from understanding how a particular gene contributes to the development of the issues in Alzheimer's disease and in developing a medication to address that issue can take many years.
Prognosis
At the current time, there are only a few medications that are approved for the treatment of Alzheimer's disease. It is important to understand that these medications do not reverse or cure the disease. People who have Alzheimer's disease may live between one to twenty years after they are diagnosed with the disorder. The average length of time people live after the diagnosis is made is about eight years. However, there can be quite a bit of variation from person-to-person. Most often people with Alzheimer's disease die from other medical conditions that are complications of the disorder including pneumonia or from other factors such as heart disease.
Resources
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Articles
- Introduction & Causes of Cognitive Disorders
- Dementia
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Alzheimer's Disease
- Alzheimer's Disease
- Prevalence and Causes of Alzheimer's Disease
- Causes of Alzheimer's Disease Continued
- Risk Factors for Alzheimer's Disease
- Symptoms of Alzheimer's Disease
- Warning Signs of Alzheimer's Disease
- Diagnosis of Alzheimer's Disease
- Diagnosis of Alzheimer's Disease - Imaging Procedures and Psychological Evaluation
- Diagnosis of Alzheimer's Disease - Neuropsychological Testing
- Treatment of Cognitive and Behavioral Symptoms associated with Alzheimer's Disease
- Research and Prognosis on Alzheimer's Disease
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Other Cognitive Disorders
- Vascular Neurocognitive Disorder
- Vascular Neurocognitive Disorder Continued
- Lewy Body Dementia
- Symptoms of Lewy Body Dementia
- Diagnosis and Treatment of Lewy Body Dementia
- Reversible Cognitive Disorder - Dementia Syndrome of Depression
- Neurocognitive Disorder Due to Another Medical Condition
- Reversible Cognitive Disorder - Delirium
- Prevention of Dementia and Other Cognitive Disorders
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Dementia Coping Skills & Behavior Management
- Coping Skills for Those With Dementia
- Coping Skills for Dementia Caregivers
- Services for Dementia Caregivers
- Communication Tips for Dementia Caregivers
- Behavioral Management for Dementia Caregivers
- Behavioral Management for Dementia Caregivers Continued
- Tips for Dealing with Specific Dementia Problematic Behaviors
- Tips for Dealing with Specific Dementia Problematic Behaviors Continued
- Traumatic Brain Injury (TBI)
- Conclusion and Resources
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- Alive with Alzheimer's
- Alzheimer's
- Days With My Father
- Decision Making, Personhood and Dementia
- Dementia
- Dementia Caregivers Share Their Stories
- Hearing the Person With Dementia
- How We Think About Dementia
- Inside Assisted Living
- Mild Cognitive Impairment and Early Alzheimer's Disease
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- Mom's OK, She Just Forgets
- My Book about Brains, Change and Dementia
- Nothing about us, without us!
- Remembering Home
- Rights, Risk and Restraint-Free Care of Older People
- Speaking Our Minds: Revised Edition
- Still Alice
- Telling Tales About Dementia
- The Almost Moon
- The Emotional Journey of the Alzheimer's Family
- The Enduring Self in People with Alzheimer's
- The Story of My Father
- Voices Of Alzheimer's
- When It Gets Dark
- When Someone You Know Is Living in a Dementia Care Community
- Wrinkles
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Links
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Videos
- Overview of Dementia with Lewy Bodies
- Common Challenges: Driving
- Diagnosis and Management of Vascular Dementia
- Difference Between Alzheimer's and Dementia
- Why Early Detection of Alzheimer’s Disease Matters
- Looking Beyond Alzheimer’s Disease: An Overview of Other Major Forms of Neurodegenerative Disease
- New Definition of Alzheimer’s Changes How Disease Is Researched
- Lewy Body Dementia: Most Common Disorder You’ve Never Heard Of
- Living With Traumatic Brain Injury
- Early Detection of Alzheimer's Disease
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37 more
- Seeing Alzheimer's in a New Way
- Inside Alzheimer’s disease
- Alzheimer's Screening
- Neurology: Testing for Alzheimer's
- Alzheimer's and Dementia Caregiver Training: Sexually Inappropriate Behaviors
- Alzheimer's and Dementia Caregiver Training: Depression/Apathy
- Alzheimer's and Dementia Caregiver Training: Agitation and Anxiety
- Alzheimer's and Dementia Caregiver Training: Aggressive Language/Behavior
- Alzheimer's and Dementia Caregiver Training: Sleep Disturbances
- Alzheimer's and Dementia Caregiver Training: Repetitive Phone Calls
- Alzheimer's and Dementia Caregiver Training: Home Safety
- Best Practices & Emerging Therapies for Patients with Alzheimer’s Disease
- Recognizing the Early Signs of Dementia
- Effective Treatments and Prevention of Alzheimer’s Disease: The Time is Now - Research on Aging
- Dementia – it affects us all
- Falls Prevention in People with Dementia
- Caregiver Training Part I: Introduction
- Caregiver Training Part II: Hallucinations
- Caregiver Training Part III: Refusal to Bathe
- Caregiver Training Part IV: Refusal to Take Medication
- Caregiver Training Part V: Repetitive Behaviors
- Caregiver Training Part VI: Repetitive Questions
- Caregiver Training Part VII: Sundowning
- Caregiver Training Part VIII: Wandering
- The Benefits of Early Detection of Alzheimer's Disease
- A New Way To Look At Alzheimer's
- The Healing Power of Music
- Falls Prevention in People with Dementia
- Falls Prevention in People with Dementia
- Protecting & Caring for Patients with Dementia
- Dementia 101 in 101 Seconds
- Normal and Abnormal Aging and the Brain
- Alzheimer’s Disease and Parkinson’s Disease
- Aggressive Behavior in People with Dementia
- Diagnosing Alzheimer’s
- Signs of Alzheimer’s
- Practical Tips for Travelling with a Loved One with Alzheimer's Disease
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